Repetitivní transkraniální magnetická stimulace (rTMS)

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Autoři: Klírová Monika, Novák Tomáš, Buday Jozef

Garant: Klírová Monika

Oponent: Kašpárek Tomáš, Ustohal Libor

Vysvětlivky:
ovál - nadpis 
kosočtverec - výběr z více variant

Shrnutí

RTMS je bezpečná a dobře snášená léčebná metoda, která se využívá jak v monoterapii, tak jako augmentační léčba. Podle aktuálních evropských doporučení je rTMS stanovena jako účinná metoda v léčbě depresivní poruchy, PTSD, auditivních halucinací a negativních symptomů u schizofrenie, OCD, cravingu u závislosti na nikotinu a v kombinaci rTMS s kognitivním tréninkem v léčbě časného stádia Alzheimerovy choroby. Dle Hydeho metaanalýzy je rTMS navíc potvrzena jako účinná metoda v léčbě generalizované úzkostné poruchy. Pro dosažení léčebného efektu rTMS jsou doporučovány léčebné protokoly o aplikaci 10 až 20 rTMS sezení.

Důkaz účinku léčby: úroveň A – definitivní (ne)účinnost, úroveň B – pravděpodobná (ne)účinnost, úroveň C – potenciální (ne)účinnost; AD – antidepresiva, PTSD – posttraumatická stresová porucha, OCD – obsedantně kompulzivní porucha, rTMS – repetitivní transkraniální magnetická stimulace, HF-rTMS – vysokofrekvenční rTMS, LF-rTMS – nízkofrekvenční rTMS, TBS – theta burst stimulace, cTBS – kontinuální TBS; iTBS – intermitentní TBS, L-DLPFC – levý dorzolaterální prefrontální kortex, P-DLPFC – pravý dorzolaterální prefrontální kortex, L-TPC – levý temporoparietální kortex (přejato a upraveno z Lefaucheur et al., 2020).

Literatura

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Datum zveřejnění: 15.1.2023